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Bioactive molecules >
MK-5172 is a novel P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
Clemizole is a H1 histamine receptor antagonist.Recently, researchers have identified that clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus replication.
Ledipasvir (GS5885) acetone is an inhibitor of the hepatitis C virus NS5A protein, which is an experimental drug for the treatment of hepatitis C.
Ledipasvir (CS-5885) is an inhibitor of the hepatitis C virus NS5A protein and is a drug for the treatment of hepatitis C.The ledipasvir/sofosbuvir combination is a direct-acting antiviral agent that interferes with HCV replication.
Asunaprevir (BMS-650032) is a potent hepatitis C virus (HCV) NS3 protease inhibitor. It was evaluated for safety, antiviral activity, and resistance in four double-blind, placebo-controlled ...
Narlaprevir (SCH 900518) is a potent, selective, orally bioavailable NS3 protease inhibitor(Ki=6 nM; EC90=40 nM).
Sofosbuvir (PSI-977, GS7977) is a drug used for hepatitis C virus (HCV) infection, with a high cure rate. It inhibits the RNA polymerase that the hepatitis C virus uses to replicate its RNA.
Simeprevir (TMC 435350) is a potent inhibitor of HCV NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM).
Telaprevir (VX-950) is a pharmaceutical drug for the treatment of hepatitis C. It is a member of a class of antiviral drugs known as protease inhibitors.
Boceprevir (EBP 520, SCH 503034) is a protease inhibitor used as a treatment for hepatitis C genotype 1. It binds to HCV nonstructural 3 NS3 (HCV) active site.
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